I'm another who wears glasses all the time. I have 2 pairs I alternate between with the same prescription - one with thick, dark plastic frames in tortoiseshell and one with thin, wire frames in dark purple - and I love eye makeup. I don't usually wear foundation or powder and I don't think I have ever worn rouge, but I do like eye makeup and tinted lip-gloss.
Like the others have said, I also do bold eyes and neutral lips. I like to save the heavy liners and darker eye makeup for when I'm wearing my plastic frames, as it can look like a bit much with the smaller wire frames.